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Los Angeles Brain and Spine Institute Surgeon Using New Liquid Treatment for Brain Aneurysms

A balloon is placed across the aneurysm, a tiny aneurysm enters the catheter and onyx is injected.
A balloon is placed across the aneurysm, a tiny aneurysm enters the catheter and onyx is injected.

The Los Angeles Brain and Spine Institute today announced that Dr. George Rappard, a neurointerventional surgeon in Glendale, California is the first physician west of the Rockies to treat a patient using an FDA-approved liquid system for treating wide-necked brain aneurysms.

Glendale, Calif. (PRWEB) October 22, 2008 -- The Los Angeles Brain and Spine Institute today announced that Dr. George Rappard, a neurointerventional surgeon in Glendale, California is the first physician west of the Rockies to treat a patient using an FDA-approved liquid system for treating wide-necked brain aneurysms.

Dr. Rappard is one of only a few physicians nationwide that are presently exploring the use of a liquid embolic system to fill wide-necked brain aneurysms, which have a wide opening where the aneurysm arises from the artery or blood vessel. A brain aneurysm is a weakness in a major blood vessel that causes a portion of the vessel wall to balloon out. This abnormality puts an individual at risk should the aneurysm break open and bleed.

"A wide-necked brain aneurysm occurs in about 25 percent of patients with brain aneurysms," said Dr. Rappard. "Wide-necked aneurysms can be difficult to treat surgically, which requires removal of bone and manipulation of the brain. However, by using a new liquid treatment called Onyx HD 500 (http://www.ev3.net/peripheral/onyx-hd500-liquid-embolic-system.htm#nogo), we are able to use a minimally invasive endovascular procedure to treat the aneurysm from within the blood vessel."

To date, there have been no research studies conducted to show whether this new liquid system is effective for treating wide-neck aneurysms, but initial clinical results are encouraging.

Dr. Rappard continued, "The potential benefit of the liquid embolic system may be the complete blockage of the blood supply to the aneurysm. This would make a recurrence of the aneurysm less likely than seen with current treatment methods. It may also help to correct or lessen some symptoms."

Until now, the only minimally invasive option available for treating brain aneurysms was coiling. In the coiling procedure, the surgeon will navigate a small catheter from the groin to the brain aneurysm and fill the aneurysm with metallic coils, causing clotting of the aneurysm. However, there is the possibility that the clot may dissolve, resulting in a recurrence of the aneurysm. In addition, some wide-necked aneurysms have such a large opening that the coils may not stay inside the aneurysm sac. In contrast to coiling, by filling the aneurysm sac or pocket with the Onyx liquid, which solidifies in minutes, blood flow into the aneurysm is blocked, helping to prevent the aneurysm from rupturing or increasing in size.

The release of the liquid treatment was preceded by a lengthy period of education and training for a small group of leading U.S. neurovascular specialists. Glendale Adventist Medical Center is one of about 25 hospitals in the United States to perform this procedure as an alternative to conventional surgery.

The new Onyx liquid treatment has been FDA approved under a Humanitarian Device Exemption from the U.S. Food & Drug Administration, which allows physicians to use the liquid to treat a disease or condition that affects fewer than 4,000 individuals in the United States per year and for which no comparable device is available. To qualify for treatment, patients must possess intracranial, saccular, sidewall aneurysms that present with a wide neck (e 4 mm) or with a dome-to-neck ratio < 2 that are not amenable to treatment with surgical clipping.

More information on brain aneurysms can be found at the following Web sites:

The National Institute of Neurological Disorders and Stroke (NINDS) http://www.ninds.nih.gov

American Stroke Association

http://www.strokeassociation.org

Society of Neurointerventional Surgery

http://www.snisonline.org

About the Los Angeles Brain and Spine Institute

The Los Angeles Brain and Spine Institute was founded in 2005, as the Valley Neuroscience Institute (www.thevni.com). The Institute fosters comprehensive neurological care to all patients. The institute offers state of the art minimally invasive brain and spine therapies, a seasoned and experienced multi-disciplinary team and cutting-edge clinical research studies. Our care is delivered in a compassionate and accessible community based setting.

Source: The Los Angeles Brain and Spine Institute

CONTACT INFORMATION:

The Los Angeles Brain and Spine Institute

(818)244-4434 (office)

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