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Synamatix Announces Collaboration with Emory University on Small RNA Based Brain Disease Studies

Synamatix announced today a research collaboration based upon neurological disease analysis with the Emory University School of Medicine. Synamatix's role in this research will be to apply its novel SynaBASE™ and SXOligoSearch™ pattern-finding applications to process and analyse small RNAs generated from mouse brain cognitive disease studies.

Kuala Lumpur (PRWEB) November 7, 2007 -- Synamatix announced today a research collaboration based upon neurological disease analysis with the Emory University School of Medicine in Atlanta, Georgia. Synamatix's role in this research will be to apply its novel SynaBASE™ and SXOligoSearch™ pattern-finding applications to process and analyse small RNAs generated from mouse brain cognitive disease studies.

Dr. Peng Jin who is the project head from the Department of Human Genetics at Emory University stated, "We are interested in studying the small RNA profile in (the) adult mouse brain. Our aim is to conduct transcription profiling in mouse brains and identify novel RNAs for future studies in brain disease. Synamatix was approached as we believe that their technologies and early-stage experience in the analysis of data from 2nd generation sequencers would greatly assist us in enhancing our research agenda.

So far, by utilising Synamatix's unique platform and approach, we have identified an increased number of novel hits, thereby adding immediate value to our project."

Synamatix General Manager, Dr Arif Anwar, commented, "This project is bound to have a significant impact on the study of potential genetic factors in brain diseases. We are pleased to have the opportunity to work with Emory University, especially in supporting such a critically significant research area. Since the release of SXOligoSearch earlier in the year we have seen continuous improvement in its performance. We are currently developing new tools and applications to accomplish our goal of being a common informatics platform for any type of sequence data. This will further support and facilitate various projects that are leveraging recent advances in genomics technologies."

SXOligoSearch, which is built upon the SynaBASE structured-network pattern platform, aligns complete reads rather than HSPs, resulting in higher specificity and sensitivity. This application is also able to handle low-quality reads containing numerous mismatches, insertions or deletions with high accuracy and superior performance.

The SynaBASE engine is a novel approach towards enhancing the scalability, sensitivity and performance of genomics research without requiring the use of expensive specialist computer hardware typically required for such work.

A trial version of SXOligoSearch is available online at www.synamatix.com. Various online bioinformatics tools based upon SynaBASE are also available for free at www.mgrc.com.my.

About Synamatix
The fundamental technology underlying Synamatix R&D is the proprietary "SynaBASE™" platform. Applications built upon this database platform exhibit very significant improvement in analysis scalability, sensitivity and performance. Synamatix is a privately held bioinformatics company whose primary activities are ongoing R&D related to its core technology, and the support of its user base in the USA, Europe, Asia and Australia.

About Emory University
Emory University is located in Atlanta. Georgia, USA and is home to nine major academic divisions, numerous centres for advanced studies, and a host of prestigious affiliated institutions. The University encompasses a graduate school of arts and sciences; professional schools of medicine, theology, law, nursing, public health, and business; and two colleges.

Contact
Patricia Chan
Marketing and Communications
Synamatix Sdn. Bhd.
enquiries @ synamatix.com
www.synamatix.com

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